Military halts clashes as political crisis grips Egypt


CAIRO (Reuters) - Egypt's Islamist president, Mohamed Mursi, called on Thursday for a national dialogue after deadly clashes around his palace, where demonstrators responded by demanding the "downfall of the regime", using the chants that brought down Hosni Mubarak.


Mursi said in a televised speech that plans for a referendum on a new constitution on December 15 were on track, proposing a meeting on Saturday with political leaders, "revolutionary youth" and legal figures to discuss the way forward after that.


The Republican Guard intervened on Thursday to halt violence outside the palace, where seven people were killed overnight in clashes between supporters and opponents of Mursi.


Members of the main opposition coalition, the National Salvation Front, said they were assessing the offer of talks to end a crisis sparked by Mursi's November 22 decree awarding himself wide powers and protecting his decisions from judicial review.


The opposition has previously demanded that Mursi scrap his decree, postpone the referendum and redraft the constitution.


As well as drawing up a political roadmap, Mursi said the talks would aim to resolve the fate of the upper house of parliament after the Islamist-dominated lower house was dissolved in June, the election law and other issues.


"I call for a full, productive dialogue with all figures and heads of parties, revolutionary youth and senior legal figures to meet this Saturday," Mursi declared, adding that the meeting would be at his official palace.


Several thousand opposition protesters near the palace waved their shoes in derision after his speech and shouted "Killer, killer" and "We won't go, he will go" - another of the slogans used against Mubarak in last year's revolt.


The Cairo headquarters of the Muslim Brotherhood, the group that propelled Mursi to victory in a June election, was set ablaze. Other offices of its political party were attacked.


This week's violence reflects the widening rifts in the most populous Arab nation, where contrasting visions of Islamists and their liberal rivals have complicated a struggle to embed democracy after Mubarak's 30 years of one-man rule.


TENTATIVE CONCESSION


The United States, worried about the stability of an Arab partner which has a peace deal with Israel and which receives $1.3 billion a year in U.S. military aid, had urged dialogue.


Mursi said he did not insist on keeping his actions shielded from legal challenge, adding that his entire decree would lapse after the constitutional referendum, regardless of its result.


He said a new constituent assembly would be formed to redraft the constitution if Egyptians rejected the one written in the past six months by an assembly dominated by Islamists.


The Republican Guard, an elite unit whose duties include protecting the presidential palace, had ordered rival demonstrators to leave by mid-afternoon. Mursi supporters withdrew, but opposition protesters remained, kept away by a barbed wire barricade guarded by tanks.


By evening their numbers had swelled to several thousand.


The military played a big role in removing Mubarak during last year's popular revolt, taking over to manage a transitional period, but had stayed out of the latest crisis.


Thousands of supporters and opponents of Mursi had fought well into Thursday's early hours, using rocks, petrol bombs and guns. Officials said 350 were wounded in the violence. Six of the dead were Mursi supporters, the Muslim Brotherhood said.


Prosecutors investigating the unrest said Brotherhood members had detained 49 wounded protesters and were refusing to release them to the authorities, the state news agency said. The Brotherhood denied this, saying all "thugs" detained by its members had been handed over to police or the Republican Guard.


"MILITIA REGIME"


Before Mursi's speech, opposition groups had called for protests after Friday prayers aimed at "the downfall of the militia regime", a dig at what they see as the Brotherhood's organized street muscle.


A communique from a leftist group urged protesters to gather at mosques and squares across Egypt, and to stage marches in Cairo and its sister city Giza, converging on the presidential palace. "Egyptian blood is a red line," the communique said.


Hardline Islamist Salafis summoned their supporters to protest against what they consider biased coverage of the crisis by some private Egyptian satellite television channels.


Outside Cairo, supporters and opponents of Mursi clashed in his home town of Zagazig in the Nile Delta, state TV reported.


Egypt plunged into renewed turmoil after Mursi issued his November 22 decree and an Islamist-dominated assembly hastily approved a new constitution to go to next week's referendum.


Since then six of the president's advisers have resigned. Essam al-Amir, the director of state television, quit on Thursday, as did a Christian official working at the presidency.


The Brotherhood's supreme guide, Mohamed Badie, called for unity, saying divisions "only serve the nation's enemies".


Mursi's opponents accuse him of seeking to create a new "dictatorship". The president says his actions were necessary to prevent courts still full of judges appointed by Mubarak from derailing a constitution vital for Egypt's political transition.


U.N. Human Rights Commissioner Navi Pillay urged the Egyptian authorities to protect peaceful protesters and prosecute anyone inciting violence, including politicians.


The Islamists, who have won presidential and parliamentary elections since Mubarak was overthrown, are confident they can win the referendum and the parliamentary election to follow.


As well as relying on his Brotherhood power base, Mursi may also tap into a popular yearning for stability and economic revival after almost two years of political turmoil.


Egypt's pound hit an eight-year low on Thursday, after previously firming on hopes that a $4.8 billion IMF loan would stabilize the economy. The stock market fell 4.6 percent.


(Additional reporting by Tom Perry, Edmund Blair and Marwa Awad; Writing by Alistair Lyon)



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Facebook might buy Microsoft’s Atlas Ad platform to compete with Google












Is Facebook (FB) preparing to compete with Google (GOOG) in online advertising? According to AllThingsD and BusinessInsider’s sources Facebook might be taking steps to build its own advertising network for online websites. AllThingsD says that rather than build a new advertising network from scratch, Facebook could just buy Microsoft’s (MSFT) Atlas Solutions platform “that already delivers billions of ad impressions a day.”


BusinessInsider reports that Facebook will reportedly pay a lower price than the $ 6 billion that Microsoft paid for aQuantive in 2007 that included Atlas Solutions. It’s estimated that Atlas is worth more than $ 30 million — a small price to pay to compete with Google’s DoubleClick ad network.












So why is Facebook interested in advertising now? Well, it’s got over 1 billion active users with emails, phone numbers, and unprecedented amounts of “likes.” As BusinessInsider puts itFacebook has so much data it could “tell marketers whether or not a Facebook user saw, on Facebook.com, an ad for a product before going to the store and buying it.”


Get more from BGR.com: Follow us on Twitter, Facebook


Social Media News Headlines – Yahoo! News


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Randy Travis Has 'Given Up Alcohol,' Will Hit Awards Show Stage















12/06/2012 at 04:30 PM EST



Randy Travis is easing back into the spotlight four months after he was arrested while nude and allegedly drunk and belligerent on a Texas highway.

The country star, 53, is performing Friday night at the American Giving Awards in Pasadena for a show airing Saturday night on NBC. This follows his November appearance on CMT Crossroads with the Avett Brothers.

"Randy is doing great. Life is good," says his lawyer Larry Friedman. "He's given up drinking alcohol. He's drinking eight glasses of water a day or more. He's on a strict exercise regimen. … He's in the best shape he's ever been in in his life."

The AGAs, hosted by Joel McHale, is a celebrity tribute to local heroes, with five charities sharing $2 million in grants. Glenn Close will receive the AGA Leadership Award.

"It's an honor being chosen as a performer for this year's American Giving Awards," Travis says in a statement. "The act of giving back to the community is priceless and something that I truly believe in."

While Travis's case is pending, he remains busy in the studio, according to his lawyer.

"He's got 31 new songs," says Friedman. "He did it at a recording studio in Texas. He used his own band. These are all old-time favorites by Hank Williams, Willie Nelson, Merle Haggard, these are the songs that he grew up with that he loved."

Reporting by KEVEN O'DONNELL

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Celebrations planned as Wash. legalizes marijuana


SEATTLE (AP) — Legal marijuana possession becomes a reality under Washington state law on Thursday, and some people planned to celebrate the new law by breaking it.


Voters in Washington and Colorado last month made those the first states to decriminalize and regulate the recreational use of marijuana. Washington's law takes effect Thursday and allows adults to have up to an ounce of pot — but it bans public use of marijuana, which is punishable by a fine, just like drinking in public.


Nevertheless, some people planned to gather at 12:01 a.m. PST Thursday to smoke in public beneath Seattle's Space Needle. Others planned a midnight party outside the Seattle headquarters of Hempfest, the 21-year-old festival that attracts tens of thousands of pot fans every summer.


"This is a big day because all our lives we've been living under the iron curtain of prohibition," said Hempfest director Vivian McPeak. "The whole world sees that prohibition just took a body blow."


In another sweeping change for Washington, Gov. Chris Gregoire on Wednesday signed into law a measure that legalizes same-sex marriage. The state joins several others that allow gay and lesbian couples to wed.


That law also takes effect Thursday, when gay and lesbian couples can start picking up their wedding certificates and licenses at county auditors' offices. Those offices in King County, the state's largest and home to Seattle, and Thurston County, home to the state capital of Olympia, planned to open the earliest, at 12:01 a.m. Thursday, to start issuing marriage licenses. Because the state has a three-day waiting period, the earliest that weddings can take place is Sunday.


The Seattle Police Department provided this public marijuana use enforcement guidance to its officers via email Wednesday night: "Until further notice, officers shall not take any enforcement action — other than to issue a verbal warning — for a violation of Initiative 502."


Thanks to a 2003 law, marijuana enforcement remains the department's lowest priority. Even before I-502 passed on Nov. 6, police rarely busted people at Hempfest, despite widespread pot use, and the city attorney here doesn't prosecute people for having small amounts of marijuana.


Officers will be advising people to take their weed inside, police spokesman Jonah Spangenthal-Lee wrote on the SPD Blotter. "The police department believes that, under state law, you may responsibly get baked, order some pizzas and enjoy a 'Lord of the Rings' marathon in the privacy of your own home, if you want to."


Washington's new law decriminalizes possession of up to an ounce for those over 21, but for now selling marijuana remains illegal. I-502 gives the state a year to come up with a system of state-licensed growers, processors and retail stores, with the marijuana taxed 25 percent at each stage. Analysts have estimated that a legal pot market could bring Washington hundreds of millions of dollars a year in new tax revenue for schools, health care and basic government functions.


But marijuana remains illegal under federal law. That means federal agents can still arrest people for it, and it's banned from federal properties, including military bases and national parks.


The Justice Department has not said whether it will sue to try to block the regulatory schemes in Washington and Colorado from taking effect.


"The department's responsibility to enforce the Controlled Substances Act remains unchanged," said a statement issued Wednesday by the Seattle U.S. attorney's office. "Neither states nor the executive branch can nullify a statute passed by Congress" — a non-issue, since the measures passed in Washington and Colorado don't "nullify" federal law, which federal agents remain free to enforce.


The legal question is whether the establishment of a regulated marijuana market would "frustrate the purpose" of the federal pot prohibition, and many constitutional law scholars say it very likely would.


That leaves the political question of whether the administration wants to try to block the regulatory system, even though it would remain legal to possess up to an ounce of marijuana.


Colorado's measure, as far as decriminalizing possession goes, is set to take effect by Jan. 5. That state's regulatory scheme is due to be up and running by October 2013.


___(equals)


Johnson can be reached at https://twitter.com/GeneAPseattle


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Dow, S&P end higher, but Apple sinks Nasdaq in wild day

NEW YORK (Reuters) - A volatile trading session ended with stocks mostly higher on Wednesday, even as Apple, the most valuable company in the United States, suffered its worst day of losses in almost four years.


In a strange occurrence, Apple accounted for the entirety of the Nasdaq 100's <.ndx> fall of 1.1 percent, while the Dow industrials - which do not include Apple as a component - enjoyed the best day since November 28.


With the drop, Apple shed nearly $35 billion in market capitalization, its biggest one-day market-cap loss ever. The company's market value, or market capitalization, now stands at $506.85 billion.


"Today's move is because of index weightings, with the Nasdaq down because of Apple's decline," said Rex Macey, chief investment officer of Wilmington Trust in Atlanta. "The S&P is up because Apple isn't as big a weight in that index, and the Dow is up even more because it isn't there at all."


The broad market seesawed, with the S&P 500 dropping into negative territory before it rebounded off the 1,400 level, seen as a key support point over the past two weeks. Investors cited comments from President Barack Obama suggesting a potential near-term resolution to the "fiscal cliff" wrangling in Washington as a catalyst for the rebound.


Shares of The Travelers Cos Inc rose 4.9 percent to $74. The stock ranked as the Dow's top percentage gainer after the insurance company said it intended to resume stock buybacks it had temporarily suspended while it assessed its exposure to Superstorm Sandy. The company also said a preliminary estimate of net losses from Sandy was about $650 million after tax.


The Dow Jones industrial average <.dji> rose 82.71 points, or 0.64 percent, to 13,034.49 at the close. The Standard & Poor's 500 Index <.spx> gained 2.23 points, or 0.16 percent, to 1,409.28. But the Nasdaq Composite Index <.ixic> fell 22.99 points, or 0.77 percent, to end at 2,973.70.


Apple, the largest U.S. company by market capitalization and a big weight in both the S&P 500 and the Nasdaq, fell 6.4 percent to $538.79. Apple is down more than 20 percent from an all-time high reached in late September, putting the stock into bear market territory.


Banking shares were led higher by a 6.3 percent jump in Citigroup to $36.46 after the company said it would cut 4 percent of its workforce. [ID:nL1E8N52IQ] The S&P financial sector index <.gspf> climbed 1.3 percent, and Bank of America hit a 52-week high of $10.55 before pulling back slightly. The stock, a Dow component, ended at $10.46, up 5.7 percent for the day.


Still, Apple struggled throughout the session. Market participants cited a host of reasons for the drop in the iPad maker's stock, including a consultant's report about the company losing share in the tablet market and reports that margin requirements had been raised by at least one clearing firm, as well as year-end tax selling ahead of a possible rise in capital-gains tax rates next year.


On the Washington front, Obama told the Business Roundtable, a group of chief executives, on Wednesday that a fiscal cliff deal was possible "in about a week" if Republicans acknowledged the need to raise taxes on the wealthiest Americans.


Equities have struggled to gain ground recently because of concerns over the fiscal cliff - a series of mandatory spending cuts and tax increases effective in early January that could push the U.S. economy into recession next year. Recently equities have moved on any whiffs of sentiment from Washington in headlines about negotiations.


"Obama's comments generated a lot of optimism, but to the extent the market believes them, that's how much we're setting ourselves up for a decline if that deadline passes with no progress," said Macey, who helps oversee about $20 billion in assets.


In an interview on CNBC after the market closed, U.S. Treasury Secretary Tim Geithner said that uncertainty over the fiscal cliff was standing in the way of stronger economic growth, and that there was no prospect for an agreement if tax rates didn't rise on the wealthiest taxpayers.


The stock of Freeport-McMoRan Copper & Gold Inc fell 16 percent to $32.17 and ranked as the S&P 500's biggest percentage decliner. The company said it was acquiring Plains Exploration & Production Co and McMoRan Exploration Co in two separate deals for $9 billion in cash and stock in a major expansion into energy.


McMoRan Exploration soared 87 percent to $15.82 and Plains surged 23.4 percent to $44.50.


After the closing bell, Standard & Poor's said it cut Greece's sovereign long-term foreign currency rating to "selective default" from its already low "C" rating. Last week, the country and its international lenders reached a deal to lower its debt burden through a debt buyback.


About half of the stocks traded on the New York Stock Exchange closed in positive territory, while about 54 percent of Nasdaq-listed shares ended lower.


Volume was higher than it has been in recent sessions, with about 7.01 billion shares changing hands on the New York Stock Exchange, the Nasdaq and NYSE MKT, above the daily average so far this year of about 6.48 billion shares.


(Editing by Jan Paschal)



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Clashes erupt in Egypt despite proposal to end crisis


CAIRO (Reuters) - Islamists fought protesters outside the Egyptian president's palace on Wednesday, while inside the building his deputy proposed a way to end a crisis over a draft constitution that has split the most populous Arab nation.


Stones and petrol bombs flew between opposition protesters and supporters of President Mohamed Mursi, and the Interior Ministry said 32 people had been arrested and three police vehicles destroyed.


Two Islamists were hit in the legs by what their friends said were bullets fired during clashes in streets around the compound in northern Cairo. One of them was bleeding heavily. And a leftist group said Islamists had cut off the ear of one of its members.


Medical sources said 33 people had been wounded, but despite reports of fatalities, the Health Ministry said there had been no deaths.


Riot police were deployed between the two sides in Cairo to try to stop confrontations that flared after dark despite an attempt by Vice President Mahmoud Mekky to ease the crisis.


Mekky said amendments to disputed articles in the draft constitution could be agreed with the opposition. A written agreement could then be submitted to the next parliament, to be elected after a referendum on the constitution on December 15.


"There must be consensus," he told a news conference, saying opposition demands had to be respected to reach a solution.


Prime Minister Hisham Kandil called for calm to "give the opportunity" for efforts underway to start a national dialogue.


Facing the gravest crisis of his six-month-old tenure, Mursi has shown no sign of buckling to the protests, confident that Islamists can win the referendum and a parliamentary election to follow.


Many Egyptians yearn for an end to political upheaval that began with the overthrow of Hosni Mubarak in February 2011 and which has hurt the economy as investors and tourists have fled.


Protests spread to other cities, and offices of the Brotherhood's political party in Ismailia and Suez were torched.


Egypt's opposition coalition blamed Mursi for the violence and said it was ready for dialogue if the Islamist leader scrapped a decree he issued on November 22 that gave him wide powers and shielded his decisions from judicial review.


DIALOGUE


"We hold President Mursi and his government completely responsible for the violence happening in Egypt today," opposition coordinator Mohamed ElBaradei told a news conference.


"We are ready for dialogue if the constitutional decree is cancelled ... and the referendum on this constitution is postponed," he said of the document written by an Islamist-led assembly that the opposition says ignores its concerns.


But liberals, leftists, Christians, ex-Mubarak followers and others opposed to Mursi have yet to generate a mass movement or a grassroots base to challenge the Brotherhood, which has come out on top in two elections since Mubarak's overthrow.


"Today what is happening in the Egyptian street, polarisation and division, is something that could and is actually drawing us to violence and could draw us to something worse," said ElBaradei, the former head of the U.N. nuclear watchdog.


Opposition leaders have previously urged Mursi to retract the November 22 decree, defer the referendum and agree to revise the constitution, but have not echoed calls from street protesters for his overthrow and the "downfall of the regime".


Mursi has said his decree was needed to prevent courts still full of judges appointed by ousted strongman Hosni Mubarak from derailing a constitution vital for Egypt's political transition.


Earlier on Wednesday Islamist supporters of Mursi tore down tents erected outside the presidential palace by leftist foes who had begun a sit-in there.


"They hit us and destroyed our tents. Are you happy, Mursi? Aren't we Egyptians too?" asked protester Haitham Ahmed.


Mohamed Mohy, a pro-Mursi demonstrator who was filming the scene, said: "We are here to support our president and his decisions and save our country from traitors and agents."


Mekky said street mobilisation by both sides posed a "real danger" to Egypt. "If we do not put a stop to this phenomenon right away ... where are we headed? We must calm down."


CALLS FOR RESTRAINT


U.S. Secretary of State Hillary Clinton weighed into Egypt's political debate, saying dialogue was urgently needed on the new constitution, which should "respect the rights of all citizens".


Clinton and Mursi worked together last month to broker a truce between Israel and Hamas Islamists in the Gaza Strip.


Washington is worried about rising Islamist power in Egypt, a staunch U.S. security partner under Mubarak, who preserved the U.S.-brokered peace treaty Cairo signed with Israel in 1979.


British Foreign Secretary William Hague called for restraint on all sides. He said Egypt's authorities had to make progress on the transition in an "inclusive manner" and urged dialogue.


The Muslim Brotherhood had summoned supporters to an open-ended demonstration at the presidential palace, a day after about 10,000 opposition protesters had encircled it for what organizers dubbed a "last warning" to Mursi.


State institutions, with the partial exception of the judiciary, have mostly fallen in behind Mursi.


The army, the muscle behind all previous Egyptian presidents in the republic's six-decade history, has gone back to barracks, having apparently lost its appetite to intervene in politics.


In August Mursi sacked Mubarak-era army commander and defense minister Mohamed Hussein Tantawi and removed the sweeping powers that the military council, which took over after Mubarak fell, had grabbed two months earlier.


Investors have seized on hopes that Egypt's turbulent transition, which has buffeted the economy for two years, may soon head for calmer waters, sending stocks 1.6 percent higher after a 3.5 percent rally on Tuesday.


Egypt has turned to the IMF for a $4.8 billion loan after the depletion of its foreign currency reserves. The government said on Wednesday the process was on track and its request would go to the IMF board as expected.


The board is due to review the facility on December 19.


Elijah Zarwan, a fellow with the European Council on Foreign Relations, said that if Egypt was to find a compromise solution to its crisis, it would not be through slogans and blows.


"It will be through quiet negotiation, not through dueling press conferences, street brawls, or civil strife," he said.


(Additional reporting by Tom Perry and Tamim Elyan; Writing by Alistair Lyon and Edmund Blair; Editing by Andrew Roche and Will Waterman)



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25 top-rated Facebook games from 2012












Games can be both a welcome and an annoying diversion on Facebook, the world’s most popular online social network. This year, Facebook crossed a big milestone — reaching 1 billion active users. Game companies such as “FarmVille” creator Zynga Inc. and Rovio Entertainment Ltd. of “Angry Birds” fame seek to tap into that vast base of users to gain more players for their games.


This week, Facebook Inc. issued a list of the 25 top-rated games that launched on Facebook in 2012. The company says the rankings are based on user ratings and engagement with the games. It’s the same methodology that Facebook uses to rank apps in its App Center.












Some of the games are played on Facebook’s website, while others are only on Apple Inc.‘s iOS or Google Inc.‘s Android devices using Facebook’s app.


Here’s the list:


1. “SongPop” (by FreshPlanet, on Facebook.com, iOS and Android)


2. “Dragon City” (by Social Point, on Facebook.com)


3. “Bike Race” (by Top Free Games, on iOS)


4. “Subway Surfers” (by Kiloo, on iOS and Android)


5. “Angry Birds Friends (by Rovio, on Facebook.com)


6. “FarmVille 2″ (by Zynga, on Facebook.com)


7. “Scramble with Friends” (by Zynga, on iOS)


8. “Clash of Clans” (by Supercell, on iOS)


9. “Marvel: Avengers Alliance” (by Playdom, on Facebook.com)


10. “Draw Something” (by Zynga, on iOS and Android)


11. “Hay Day” (by Supercell, on iOS)


12. “Baseball Heroes” (by Syntasia, on Facebook.com)


13. “ChefVille” (by Zynga, on Facebook.com)


14. “CSR Racing” (by NaturalMotion Games, on iOS)


15. “Candy Crush Saga” (by King.com, on Facebook.com and iOS)


16. “Matching With Friends” (by Zynga, on Facebook.com)


17. “Legend Online” (by Oasis Games, on Facebook.com)


18. “Jurassic Park Builder” (by Ludia, on Facebook.com)


19. “Dungeon Rampage” (by Rebel Entertainment, on Facebook.com)


20. “Pockie Ninja II Social” (by NGames Ltd., on Facebook.com)


21. “Jetpack Joyride” (by Halfbrick, on Facebook.com)


22. “Social Empires” (by Social Point, on Facebook.com and iOS)


23. “Bil ve Fethet” (by Peak Games, on Facebook.com)


24. “Ruby Blast Adventures” (by Zynga, on Facebook.com and iOS)


25. “Pyramid Solitaire Saga” (by King.com, on Facebook.com)


Social Media News Headlines – Yahoo! News


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Homeless Man Charged with Subway Killing















12/05/2012 at 04:30 PM EST







Suspect in N.Y.C. subway killing



A homeless man has been arrested and charged with murder for allegedly pushing a man in front of a New York subway train.

Naeem Davis, 30, implicated himself in the crime after being taken into custody and questioned by the New York Police Department on Tuesday, police spokesman Paul J. Browne tells the New York Times.

The suspect's name and the charge were made public Wednesday after witnesses who saw Davis shove Ki-Suck Han, 58, in front of the train Monday afternoon identified him in a lineup, according to police.

Han attempted to climb back up onto the platform as the train approached, a moment captured by freelance photographer R. Umar Abbasi.

The image covered the New York Post Tuesday, sparking debate over journalistic ethics and, writes the Times, raising "questions about how bystanders in the city can – and perhaps, should – behave in moments of crisis."

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Longer tamoxifen use cuts breast cancer deaths


Breast cancer patients taking the drug tamoxifen can cut their chances of having the disease come back or kill them if they stay on the pills for 10 years instead of five years as doctors recommend now, a major study finds.


The results could change treatment, especially for younger women. The findings are a surprise because earlier research suggested that taking the hormone-blocking drug for longer than five years didn't help and might even be harmful.


In the new study, researchers found that women who took tamoxifen for 10 years lowered their risk of a recurrence by 25 percent and of dying of breast cancer by 29 percent compared to those who took the pills for just five years.


In absolute terms, continuing on tamoxifen kept three additional women out of every 100 from dying of breast cancer within five to 14 years from when their disease was diagnosed. When added to the benefit from the first five years of use, a decade of tamoxifen can cut breast cancer mortality in half during the second decade after diagnosis, researchers estimate.


Some women balk at taking a preventive drug for so long, but for those at high risk of a recurrence, "this will be a convincer that they should continue," said Dr. Peter Ravdin, director of the breast cancer program at the UT Health Science Center in San Antonio.


He reviewed results of the study, which was being presented Wednesday at a breast cancer conference in San Antonio and published by the British medical journal Lancet.


"The result of this trial will have a major, immediate impact on premenopausal women," Ravdin said.


About 50,000 of the roughly 230,000 new cases of breast cancer in the United States each year occur in women before menopause. Most breast cancers are fueled by estrogen, and hormone blockers are known to cut the risk of recurrence in such cases.


Tamoxifen long was the top choice, but newer drugs called aromatase inhibitors — sold as Arimidex, Femara, Aromasin and in generic form — do the job with less risk of causing uterine cancer and other problems.


But the newer drugs don't work well before menopause. Even some women past menopause choose tamoxifen over the newer drugs, which cost more and have different side effects such as joint pain, bone loss and sexual problems.


The new study aimed to see whether over a very long time, longer treatment with tamoxifen could help.


Dr. Christina Davies of the University of Oxford in England and other researchers assigned 6,846 women who already had taken tamoxifen for five years to either stay on it or take dummy pills for another five years.


Researchers saw little difference in the groups five to nine years after diagnosis. But beyond that time, 15 percent of women who had stopped taking tamoxifen after five years had died of breast cancer versus 12 percent of those who took it for 10 years. Cancer had returned in 25 percent of women on the shorter treatment versus 21 percent of those treated longer.


Tamoxifen had some troubling side effects: Longer use nearly doubled the risk of endometrial cancer. But it rarely proved fatal, and there was no increased risk among premenopausal women in the study — the very group tamoxifen helps most.


"Overall the benefits of extended tamoxifen seemed to outweigh the risks substantially," Dr. Trevor Powles of the Cancer Centre London wrote in an editorial published with the study.


The study was sponsored by cancer research organizations in Britain and Europe, the United States Army, and AstraZeneca PLC, which makes Nolvadex, a brand of tamoxifen, which also is sold as a generic for 10 to 50 cents a day. Brand-name versions of the newer hormone blockers, aromatase inhibitors, are $300 or more per month, but generics are available for much less.


The results pose a quandary for breast cancer patients past menopause and those who become menopausal because of their treatment — the vast majority of cases. Previous studies found that starting on one of the newer hormone blockers led to fewer relapses than initial treatment with tamoxifen did.


Another study found that switching to one of the new drugs after five years of tamoxifen cut the risk of breast cancer recurrence nearly in half — more than what was seen in the new study of 10 years of tamoxifen.


"For postmenopausal women, the data still remain much stronger at this point for a switch to an aromatase inhibitor," said that study's leader, Dr. Paul Goss of Massachusetts General Hospital. He has been a paid speaker for a company that makes one of those drugs.


Women in his study have not been followed long enough to see whether switching cuts deaths from breast cancer, as 10 years of tamoxifen did. Results are expected in about a year.


The cancer conference is sponsored by the American Association for Cancer Research, Baylor College of Medicine and the UT Health Science Center.


___


Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP


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Wall Street dips as investors seek cliff progress

NEW YORK (Reuters) - Stocks finished slightly lower in a quiet session on Tuesday as the back-and-forth wrangling over the "fiscal cliff" gave investors little reason to act.


Trading volume was light as legislators continue to negotiate a deal to avoid a $600 billion package of tax hikes and federal spending cuts that would begin January 1 and could push the economy into recession.


Just 5.86 billion shares changed hands on the New York Stock Exchange, the Nasdaq and the NYSE MKT, below the year's daily average of 6.48 billion shares.


A key measure of investor anxiety has remained muted. The CBOE Volatility Index or VIX <.vix>, a gauge of market anxiety, was at 17.13, up 2.9 percent. It has not traded above 20 since July.


Optimism for progress was dented after remarks by President Barack Obama, who rejected a Republican proposal to resolve the crisis as "out of balance" and said any deal must include a rise in income tax rates on the wealthiest Americans.


"People don't know if what's going on is political posturing or real negotiations that represent progress," said Bernard Baumohl, managing director and chief global economist at the Economic Outlook Group in Princeton, New Jersey.


Expectations of higher taxes on dividends beginning in 2013 have pushed many companies to pay special dividends this year or advance their next payback to investors. Coach became the latest to move up the date of its next dividend payment, and the news lifted shares of the upscale leather-goods maker earlier in the session. By the close, though, Coach was down 1.2 percent at $57.52.


One of the S&P 500's top sectors for the day was health care <.gspa>, considered a defensive group.


The Dow Jones industrial average <.dji> fell 13.82 points, or 0.11 percent, to 12,951.78 at the close. The Standard & Poor's 500 Index <.spx> dipped 2.41 points, or 0.17 percent, to 1,407.05. The Nasdaq Composite Index <.ixic> shed 5.51 points, or 0.18 percent, to close at 2,996.69.


The market has been sensitive to rhetoric from Washington, as a failure to reach an agreement could send the U.S. economy back into recession. Still, many expect a resolution to be found, which could extend the S&P 500's rally of 12 percent so far this year.


Differences within the Republican Party came to the fore on Tuesday as one senator opposed to raising taxes lashed out at Republican House Speaker John Boehner for proposing to increase revenue by closing some tax loopholes.


Congressional Republicans recently proposed steep spending cuts to bring down the budget deficit, but gave no ground on Obama's call to raise tax rates on the rich. The proposal was quickly dismissed by the White House.


"We're on hold trying to figure it out, but investors are stressed since they have to make decisions soon about how to proceed with their investments if taxes are indeed going up. We could see a real pick-up in volume over the next week or so," Baumohl said.


Netflix Inc was the S&P 500's top percentage gainer, advancing 14 percent to $86.65 after Walt Disney Co agreed to give the company exclusive TV distribution rights to its movies, starting in 2016.


Darden Restaurants Inc shares plunged 9.6 percent to $47.40 as the S&P 500's worst performer after the company warned that its latest quarter would miss expectations after unsuccessful promotions led to a decline in sales at its Olive Garden, Red Lobster and LongHorn Steakhouse chains.


In contrast, Big Lots Inc surged 11.5 percent to $31.27 after the close-out retailer posted a smaller-than-expected loss and boosted its full-year adjusted earnings forecast.


MetroPCS Communications shares tumbled 7.5 percent to $9.96 after Sprint Nextel appeared unlikely to make a counter-offer for the wireless service provider.


Almost half of the stocks traded on the New York Stock Exchange closed lower, while 50 percent of Nasdaq-listed shares closed in negative territory.


After the closing bell, Pandora Media Inc


shares plunged 23 percent after the company reported its third-quarter results.

(Editing by Jan Paschal)

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