Microsoft's slide hits tech shares, but retailers gain

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France recognizes new Syria opposition

CAIRO/PARIS (Reuters) - France became the first European power to recognize Syria's new opposition coalition as the sole representative of its people and said on Tuesday it would look into arming rebels against President Bashar al-Assad once they form a government.

Twenty months into their bloody uprising against Assad, fragmented Syrian opposition groups struck a deal in Qatar on Sunday to form a broad coalition and their leader immediately appealed for European backing.

"I announce today that France recognizes the Syrian National Council as the sole legitimate representative of the Syrian people and as future government of a democratic Syria making it possible to bring an end to Bashar al-Assad's regime," French President Francois Hollande said, breaking ranks with European allies. Six Gulf Arab states took a similar step on Monday.

The question of arming the rebels would be looked at as soon as the rebel coalition formed a transitional government, Hollande told a news conference in Paris.

Arab League and EU foreign ministers meeting in Cairo on Tuesday welcomed the formation of the coalition as an important step forward, although their communiqué showed they had not reached a unanimous decision to recognize it as Syria's sole authority.

The French announcement came just hours after Syria's newly installed opposition leader urged European states to back the opposition so it could buy weapons.

Paris, one of Assad's harshest critics, had previously ruled out arming rebel forces, concerned that weapons could get into the hands of radical Islamists.

Speaking to Reuters as Arab and European ministers met to discuss Syria at the Arab League in Cairo, Mouaz Alkhatib, the Damascus preacher elected unopposed on Sunday to lead the new group, had asked for diplomatic backing.

"I request European states to grant political recognition to the coalition as the legitimate representative of the Syrian people and to give it financial support," he said.

"When we get political recognition, this will allow the coalition to act as a government and hence acquire weapons and this will solve our problems," added Alkhatib, who has been described by supporters as a moderate noted for his embrace of Syria's religious and ethnic minorities.

So far, concerted action on Syria has been thwarted by divisions within the opposition, as well as by big power rivalries and a regional divide between Sunni Muslim foes of Assad and his Shi'ite allies in Iran and Lebanon.

Russia and China, which have lent Assad diplomatic support since the uprising erupted in March last year, have shown no sign of warming towards his Western- and Arab-backed opponents.

"STEP FORWARD"

Cajoled by Qatar and the United States, the ineffectual Syrian National Council, previously the main opposition body based abroad, agreed to join a wider coalition on Sunday.

Britain's foreign minister, William Hague, said the coalition must show it had support within Syria before London would acknowledge it as the rightful government.

"If they have this, yes, we will then recognize them as the legitimate representative of the Syrian people," he told reporters at the Arab-European meeting in Cairo.

The opposition had hoped its new-found unity would clear the way for outside powers to arm the rebels, but Western nations fear such weapons could reach the hands of Islamist militants.

Western concern has also been heightened by documented reports of atrocities by ill-disciplined insurgents.

"Syria's newly created opposition front should send a clear message to opposition fighters that they must adhere to the laws of war and human rights law, and that violators will be held accountable," New York-based Human Rights Watch said.

BORDER VIOLENCE

Assad, whose family has ruled Syria for 42 years, has vowed to fight to the death in a conflict that has already killed an estimated 38,000 people and risks sucking in other countries.

His warplanes again struck homes in Ras al-Ain, a town on the northern border seized by rebels last week. Civilians fled over the border dividing it from the Turkish town of Ceylanpinar and thick plumes of smoke billowed upwards.

Syrian jets and artillery hit the town of Albu Kamal on the frontier with Iraq, where rebels have seized some areas, according to the mayor of the Iraqi border town of Qaim.

Tension also remained high on the Golan Heights, where Israeli gunners have retaliated against stray Syrian mortar fire landing on the occupied plateau in the previous two days.

Twenty months of conflict have created a vast humanitarian crisis, with more than 408,000 Syrians fleeing to neighboring countries and up to four million expected to need aid by early next year, according to the United Nations.

Fighting has also displaced 2.5 million civilians inside Syria, the Syrian Arab Red Crescent estimates.

"If anything, they believe it could be more; this is a very conservative estimate," Melissa Fleming, chief spokeswoman of the U.N. High Commissioner for Refugees, said in Geneva.

"So people are moving, really on the run, hiding," she told a news briefing. "They are difficult to count and access."

In Cairo, Arab League chief Nabil Elaraby urged opposition factions to join Alkhatib's group, formally known as the Syrian National Coalition for Opposition and Revolutionary Forces.

But although six Gulf Arab nations recognized the coalition as Syria's only legitimate representative on Monday, Iraq, Algeria and Lebanon prevented the League from following suit.

Iraq and Lebanon, with influential Shi'ite populations, have generally maintained better relations with Iran and with Assad, whose minority Alawite sect is an offshoot of Shi'ite Islam.

(Additional reporting by Shaimaa Fayed in Cairo and Jonathon Burch in Ceylanpinar, Turkey; Writing by Giles Elgood; Editing by Peter Graff)

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Zynga CFO leaves for Facebook

SAN FRANCISCO (Reuters) – Zynga Inc‘s chief financial officer, David Wehner, will leave the company for an executive position at Facebook Inc, the gaming company announced Tuesday as it reshuffled its upper ranks.

David Ko, chief mobile officer, has been elevated to become Zynga‘s new chief operations officer.

Mark Vranesh, Zynga’s top accounting executive, will replace Wehner as CFO, Zynga said.

(Reporting By Gerry Shih; Editing by Steve Orlofsky)

Gaming News Headlines – Yahoo! News

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Psy to Be This Year's New Media Honoree at the American Music Awards

11/13/2012 at 04:00 PM EST

Psy

Dave Hogan/MTV 2012/Getty

All the YouTube clicks have paid off for "Gangnam Style" rapper, Psy.

He became an overnight sensation in the United States, and now the Korea-bred artist, also known as Park Jae-Sang, is being honored at the American Music Awards on Sunday.

Psy will follow in the footsteps of DeStorm, Christina Grimmie and Karmin, to become this year's new media honoree for his cyber success.

He will receive a trophy for his hit single – which has racked up more than 28 million video clicks – during the Coca-Cola Red Carpet LIVE! at the 2012 AMAs pre-show. Psy will also perform his catchy tune during the show itself.

The pre-show will stream live on YouTube and other partner sites starting at 5 p.m. ET/2 p.m. PT. The 40th annual American Music Awards airs Sunday at 8 p.m. on ABC.

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Report: FDA wanted to close Mass pharmacy in 2003

WASHINGTON (AP) — Nearly a decade ago, federal health inspectors wanted to shut down the pharmacy linked to a recent deadly meningitis outbreak until it cleaned up its operations, according to congressional investigators.

About 440 people have been sickened by contaminated steroid shots distributed by New England Compounding Center, and more than 32 deaths have been reported since the outbreak began in September, according to the Centers for Disease Control and Prevention. That has put the Framingham, Mass.-based pharmacy at the center of congressional scrutiny and calls for greater regulation of compounding pharmacies, which make individualized medications for patients and have long operated in a legal gray area between state and federal laws.

The House Energy and Commerce Committee released a detailed history of NECC's regulatory troubles on Monday, ahead of a meeting Wednesday meeting to examine how the outbreak could have been prevented. The 25-page report summarizes and quotes from FDA and state inspection reports and internal memos, though the committee declined to release the original documents.

The report shows that after several years of problems, Food and Drug Administration officials in 2003 suggested that the compounding pharmacy be "prohibited from manufacturing" until it improved its operations. But FDA regulators deferred to their counterparts in Massachusetts, who ultimately reached an agreement with the pharmacy to settle concerns about the quality of its prescription injections.

The congressional report also shows that in 2003 the FDA considered the company a pharmacy. That's significant because since the outbreak came to light in late September, public health officials have charged that NECC was operating more as a manufacturer than a pharmacy, shipping thousands of doses of drugs to all 50 states instead of small batches of drugs to individual patients. Manufacturers are regulated by the FDA and are subject to stricter quality standards than pharmacies.

The report offers the most detailed account yet of the numerous regulatory complaints against the pharmacy, which nearly date back to its founding in 1998. Less than a year later, the company was cited by the state pharmacy board for providing doctors with blank prescription pads with NECC's information. Such promotional items are illegal in Massachusetts and the pharmacy's owner and director, Barry Cadden, received an informal reprimand, according to documents summarized by the committee.

Cadden was subject to several other complaints involving unprofessional conduct in coming years, but came to the FDA's attention in 2002. Here are some key events from the report highlighting the company's early troubles with state and federal authorities:

__ In March of 2002 the FDA began investigating reports that five patients had become dizzy and short of breath after receiving NECC's compounded betamethasone repository injection, a steroid used to treat joint pain and arthritis that's different from the one linked to the current meningitis outbreak.

FDA inspectors visited NECC on April 9 and said Cadden was initially cooperative in turning over records about production of the drug. But during a second day of inspections, Cadden told officials "that he was no longer willing to provide us with any additional records," according to an FDA report cited by congressional investigators. The inspectors ultimately issued a report citing NECC for poor sterility and record-keeping practices but said that "this FDA investigation could not proceed to any definitive resolution," because of "problems/barriers that were encountered throughout the inspection."

__ In October of 2002, the FDA received new reports that two patients at a Rochester, N.Y., hospital who came down with symptoms of bacterial meningitis after receiving a different NECC injection. The steroid, methylprednisolone acetate, is the same injectable linked to the current outbreak and is typically is used to treat back pain. Both patients were treated with antibiotics and eventually recovered, according to FDA documents cited by the committee.

When officials from the FDA and Massachusetts Board of Pharmacy visited NECC later in the month, Cadden said vials of the steroid returned by the hospital had tested negative for bacterial contamination. But when FDA scientists tested samples of the drug collected in New York they found bacterial contamination in four out of 14 vials sampled. It is not entirely clear whether FDA tested the same lot shipped to the Rochester hospital.

__ At a February 2003 meeting between state and federal officials, FDA staff emphasized "the potential for serious public consequences if NECC's compounding practices, in particular those relating to sterile products, are not improved." The agency issued a list of problems uncovered in its inspection to NECC, including a failure to verify if sterile drugs met safety standards.

But the agency decided to let Massachusetts officials take the lead in regulating the company, since pharmacies are typically regulated at the state level. It was decided that "the state would be in a better position to gain compliance or take regulatory action against NECC as necessary," according to a summary of the meeting quoted by investigators.

The FDA recommended the state subject NECC to a consent agreement, which would require the company to pass certain quality tests and assurances to continue operating. But congressional investigators say Massachusetts Board of Pharmacy did not take any action until "well over a year later."

__ In October 2004, the board sent a proposed consent agreement to Cadden, which would have included a formal reprimand and a three-year probationary period for the company's registration. The case ended without disciplinary action in 2006, when NECC agreed to a less stringent consent decree with the state.

FDA Commissioner Margaret Hamburg and Massachusetts Department of Public Health interim commissioner Lauren Smith are scheduled to testify at Wednesday's hearing.

According to the congressional report, lawmakers plan to ask the witnesses whether the FDA and state pharmacy board acted appropriately. Cadden is also scheduled to appear at the hearing, after lawmakers issued a subpoena to compel him to attend.

The NECC has been closed since early last month, and Massachusetts officials have taken steps to permanently revoke its license. The pharmacy has recalled all the products it makes, including 17,700 single-dose vials of a steroid that tested positive for the fungus tied to the outbreak.

Read More..

S&P 500 and Nasdaq inch higher, fiscal cliff a concern

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Syria's new opposition coalition seeks recognition

DOHA (Reuters) - Syria's new opposition leadership, painfully forged under Arab and Western pressure, set out on Monday to gather recognition and wider backing for the struggle to take over the country from President Bashar al-Assad.

Violence flared again on the Turkish border and the line separating Syria from the Israeli-occupied Golan Heights, underscoring how the conflict is spilling into the region.

Reformist Damascus cleric Mouaz Alkhatib flew to Cairo to seek the Arab League's blessing for the new assembly that unanimously elected him as its leader the day before.

Alkhatib, 50, jailed several times for criticizing Assad, fled into exile this year. He has long promoted a liberal Islam tolerant of Syria's Christian, Alawite and other minorities.

"The first step towards recognition will take place at the Arab League," he told a news conference in Doha. The body would then seek endorsement from Assad's Arab and Western foes in the "Friends of Syria" group and from the U.N. General Assembly.

Russia, which with China has foiled U.N. action on Syria and views Assad's opponents as pawns of the West, urged the new body to negotiate and to reject outside meddling.

Asked if China recognized the new coalition, Foreign Ministry spokesman Hong Lei called on all parties to initiate "a political transition process guided by the Syrian people".

Egypt, Saudi Arabia and most Arab League members want Assad removed, although some, such as Iraq, Lebanon and Algeria, take a more neutral stance on Syria, where violence raged on.

BORDER BOMBING

Israeli tanks fired shells into Syria and scored "direct hits" in response to a Syrian mortar round that struck the Golan Heights, the Israeli military said.

It was the second time in two days that Israel has responded to what it said was errant Syrian fire. On Sunday the military said it had a fired a "warning shot" across the disengagement line, while on Monday it said it had fired back at "the source".

Syria and Israel have not fought over the Golan since the 1973 Middle East conflict, but are still formally at war.

At the northern end of the country, Syrian jets and helicopters attacked the rebel-held town of Ras al-Ain, with some bombs landing just meters (yards) from the Turkish border, sending scores of civilians fleeing into Turkey.

A Reuters reporter on the border said one warplane flew right along the border and appeared to stray across it at one point, as bombs sent up plumes of black smoke.

The Syrian Observatory for Human Rights said 12 people, including seven Islamist militants, had been killed in the air strikes on Ras al-Ain, which fell to rebels on Thursday during an advance into Syria's mixed Arab and Kurdish northeast.

Another opposition group put the Ras al-Ain death toll at 16. The pro-opposition Observatory, which tracks the violence from Britain, said 140 people were killed in Syria on Sunday. More than 38,000 people have been killed since March last year.

Turkey, whose border security worries were heightened by a sudden influx of 9,000 refugees within 24 hours last week, has consulted its NATO allies about possibly deploying Patriot surface-to-air missiles to deter Syria's air force.

Such a move could be a prelude to enforcing a no-fly zone in Syria, although Western powers have fought shy of this.

Riad Seif, a respected Syrian dissident who proposed the new opposition body, said no such military intervention was needed.

"We will protect ourselves by owning developed weapons and networks of defence missiles," he said, citing what he said was a promise by the Friends of Syria to provide "methods" to counter shelling and air strikes by Assad's forces.

NATO chief Anders Fogh Rasmussen said in Prague that the alliance would "do what it takes to defend Turkey", without referring specifically to Patriot missiles.

After days of wrangling in Qatar, Syrian politicians, rebels and representatives of ethnic and religious minorities finally laid aside their disputes and, under U.S. and Qatari pressure, agreed to form the Syrian National Coalition for Opposition and Revolutionary Forces, as a prelude to a government-in-exile.

INCLUSIVE APPROACH

Alkhatib, the former imam of the Umayyad Mosque in Damascus, called on Syrian soldiers to desert and all sects to unite.

"We demand freedom for every Sunni, Alawi, Ismaili, Christian, Druze, Assyrian ... and rights for all parts of the harmonious Syrian people," the soft-spoken preacher said.

It is unclear whether the Coalition can succeed where the exile Syrian National Council (SNC) failed in overcoming the mutual suspicions and in-fighting that have weakened the nearly 20-month-old drive to end four decades of Assad family rule.

"This is a significant step forward, because they finally seem to be forging a more broadly-based platform that includes the SNC but without the SNC taking the lion's share," said Salman Shaikh, director of the Doha Brookings Center.

He said military councils fighting inside Syria should be plugged into the new political structure as a way of encouraging coordinated international support for the uprising.

"We need a unified channel of support," he said. "The United States still seems hesitant about training and arming the opposition, and I believe this is a mistake, because the U.S. has the capacity to do it more so than anyone else."

Qatar said recognition for a temporary Syrian government would allow it to seek weapons from abroad.

Washington, which promoted the Doha unity talks, hailed the outcome, promising to support the Syrian National Coalition "as it charts a course toward the end of Assad's bloody rule and the start of the peaceful, just, democratic future...".

Assad, whose Alawite minority is rooted in Shi'ite Islam, has support from Shi'ite Iran and its Lebanese Shi'ite allies, but has few friends among the region's Sunni-led nations.

With Syria enduring a bloody military stalemate almost 20 months after peaceful protests first erupted, Assad's opponents hope a more cohesive opposition can turn the tide, winning more military and diplomatic support from allies wary of the growing role of Islamist militants, some of them linked to al Qaeda.

"For the first time, there are credible multinational pledges to support the Syrian revolution, politically and logistically," said London-based Syria analyst Rima Allaf.

"With the promise of real weapons, the different groups of the Free Syrian Army are more likely to regroup under a unified opposition and command, as it is to their benefit."

She said success for the new opposition body could make the position of Russia and China irrelevant. "Their direct support of Assad may continue, perhaps until the stakes change and they see no more benefit to holding on to a losing side."

(Additional reporting by Andrew Hammond in Doha, Khaled Yacoub Oweis in Amman, Jonathon Burch in Ceylanpinar, Crispian Balmer in Jerusalem, Arshad Mohammed in Washington, Michael Martina in Beijing and Steve Gutterman in Moscow; Writing by Alistair Lyon; Editing by Giles Elgood)

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Windows Server Developers Can Now Use HP Cloud to Build, Deploy and Scale Their Applications

I am happy to share that HP Cloud Compute now supports Microsoft Windows Server 2008 instances in addition to the variety of Linux distributions that are already available. Windows Server instances can now be launched in our US-West region. Since HP Cloud Compute is in public beta, all customers receive a 50% discount (see pricing below).

It is a priority for us to provide the tools that enable developers to quickly build, test, deploy and scale their applications in the cloud. That is why we created our CLI for Windows so that developers working in a Windows Server environment can quickly launch and manage their instances using the command line.

The three Windows Server images available are the Enterprise Editions of Windows Server 2008 SP2 (32 bit), Windows Server 2008 SP2 (64 bit) and Windows Server 2008 R2 (64 bit).  All Windows Server instances are created with a randomly generated password, which is then encrypted.  You can create and manage your Windows Server instances from our console, UNIX CLI and Windows CLI. For information about how to access your Windows Server instances using Remote Desktop (RDP), please review our documentation here.

The licenses for a Windows Server instance are included in the hourly rate for your instance, so you can spin up a server and get started without needing to worry about any additional licensing concerns.  Please see the table below for details about the hourly fees for both standard HP Cloud Compute Linux Instances and HP Cloud Compute Windows Server Instances.  While HP Cloud Compute continues in public beta, all customers receive a 50% discount off the prices listed below.

HP Cloud Compute Instance Types	Linux (per hour)	Windows (per hour)
Extra Small (1GB RAM, 1 core, 30GB disk)	$ 0.04	$ 0.06
Small (2GB RAM, 2 cores, 60GB disk)	$ 0.08	$ 0.12
Medium (4GB RAM, 2 cores, 120GB disk)	$ 0.16	$ 0.24
Large (8GB RAM, 4 cores, 240GB disk)	$ 0.32	$ 0.48
Extra Large (16GB RAM, 4 cores, 480GB disk)	$ 0.64	$ 0.96
Double Extra Large (32GB RAM, 8 cores, 960GB disk)	$ 1.28	$ 1.92

Our team has been working hard to ensure that we are able to support all of your public cloud needs and appreciate all those that participated in our private and public betas.  We are very excited about the launch of Windows Server instances.  Stay tuned as we plan to launch support for additional versions of Windows Server including Windows Server 2012 in the coming months.  As always, feel free to leave a comment, connect with us on chat or email or find us on twitter (@hpcloud) if you have any questions.

Linux/Open Source News Headlines – Yahoo! News

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Reese Witherspoon, Jim Toth & Ryan Phillippe: Soccer Cheering Section

By Pernilla Cedenheim

11/12/2012 at 04:45 PM EST

Ryan Phillippe, Jim Toth and Reese Witherspoon

Ramey

They're one big happy family – at least as far as soccer is concerned.

On Saturday, Reese Witherspoon and her husband Jim Toth – who welcomed their first child together in September – were joined by her ex husband (and father of her two older kids) Ryan Phillippe on the sidelines of their son Deacon's soccer game.

"Jim and Ryan seemed to get along great," an observer tells PEOPLE of Witherspoon's current and former husbands. "They were both very involved in the game and kept cheering and clapping. Including Reese, they all seemed to have fun watching Deacon play."

From the looks of things, all three parents took an active role in being there for the 9-year-old budding athlete, who at one point left the field after he fell on his already-injured wrist.

"Everyone acted very concerned and tried to calm him down," says the observer. "Both Jim and Ryan took care of Deacon."

When the game was over, Toth and Phillippe – both dressed in casual button-down shirts and baseball hats – shook hands and said goodbye.

Ryan Phillippe and Jim Toth

Splash News Online

Witherspoon – who won an Oscar for 2005's Walk the Line – is a regular at her son's soccer matches, and even attended a game just three weeks after giving birth to her new son Tennessee James.

"Reese has been in the best mood since she gave birth to Tennessee," another source tells PEOPLE. "She recovered very quickly and has been feeling great."

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British medical journal slams Roche on Tamiflu

LONDON (AP) — A leading British medical journal is asking the drug maker Roche to release all its data on Tamiflu, claiming there is no evidence the drug can actually stop the flu.

The drug has been stockpiled by dozens of governments worldwide in case of a global flu outbreak and was widely used during the 2009 swine flu pandemic.

On Monday, one of the researchers linked to the BMJ journal called for European governments to sue Roche.

"I suggest we boycott Roche's products until they publish missing Tamiflu data," wrote Peter Gotzsche, leader of the Nordic Cochrane Centre in Copenhagen. He said governments should take legal action against Roche to get the money back that was "needlessly" spent on stockpiling Tamiflu.

Last year, Tamiflu was included in a list of "essential medicines" by the World Health Organization, a list that often prompts governments or donor agencies to buy the drug.

Tamiflu is used to treat both seasonal flu and new flu viruses like bird flu or swine flu. WHO spokesman Gregory Hartl said the agency had enough proof to warrant its use for unusual influenza viruses, like bird flu.

"We do have substantive evidence it can stop or hinder progression to severe disease like pneumonia," he said.

In the U.S., the Centers for Disease Control and Prevention recommends Tamiflu as one of two medications for treating regular flu. The other is GlaxoSmithKline's Relenza. The CDC says such antivirals can shorten the duration of symptoms and reduce the risk of complications and hospitalization.

In 2009, the BMJ and researchers at the Nordic Cochrane Centre asked Roche to make all its Tamiflu data available. At the time, Cochrane Centre scientists were commissioned by Britain to evaluate flu drugs. They found no proof that Tamiflu reduced the number of complications in people with influenza.

"Despite a public promise to release (internal company reports) for each (Tamiflu) trial...Roche has stonewalled," BMJ editor Fiona Godlee wrote in an editorial last month.

In a statement, Roche said it had complied with all legal requirements on publishing data and provided Gotzsche and his colleagues with 3,200 pages of information to answer their questions.

"Roche has made full clinical study data ... available to national health authorities according to their various requirements, so they can conduct their own analyses," the company said.

Roche says it doesn't usually release patient-level data available due to legal or confidentiality constraints. It said it did not provide the requested data to the scientists because they refused to sign a confidentiality agreement.

Roche is also being investigated by the European Medicines Agency for not properly reporting side effects, including possible deaths, for 19 drugs including Tamiflu that were used in about 80,000 patients in the U.S.

____

Online:

www.bmj.com.tamiflu/

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